Optimized design of a nanostructured SPCE-based multipurpose biosensing platform formed by ferrocene-tethered electrochemically-deposited cauliflower-shaped gold nanoparticles

• Wicem Argoubi,
• Maroua Saadaoui,
• Sami Ben Aoun and
• Noureddine Raouafi

Beilstein J. Nanotechnol. 2015, 6, 1840–1852, doi:10.3762/bjnano.6.187

• structured with cauliflower-shaped gold nanoparticles (cfAuNPs) and we show its applications in immunosensing and enzyme-based detection. The electrochemical reduction of Au(III) allows for the electrodeposition of highly dispersed cauliflower-shaped gold nanoparticles on the surface of screen-printed carbon

• pertaining to enzymatic kinetics studies. The levels of hIgG in human serum and H2O2 in honey were successfully determined and served as assessment tools of the applicability of the platforms for real samples analysis. Keywords: cauliflower-shaped gold nanoparticles; enzymatic detection; IgG sensing

• nanoparticles which agglomerate into highly dispersed, more complex, cauliflower-shaped gold nanoparticles with the increase of the number of cycles. After 15 cycles, the particulates reach an average diameter of ca. 61 nm. For electrodes modified by 15 sweeping cycles, EDX showed the presence of ca. 4.7% of